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Changelog

Source: NEWS.md

biodosetools (development version)

  • Updated citation details for {biodosetools} after publication in Int J Radiat Biol (doi:10.1080/09553002.2023.2176564).
  • Improvements in deploy-shiny.yml CI workflow.
  • Added dev/shiny-redirect shiny app to redirect biodosetools-v3 at shinyapps.io to version hosted by Bundesamt für Strahlenschutz.

biodosetools 3.6.1

CRAN release: 2022-11-16

Improvements

  • Updated LQ and L formulas to use lambda instead of Y for yield in parse_model_formula(), list_fitting_formulas(), and help dialogues.
  • Removed unnecessary {base} namespace in solve() call.
  • Removed legacy gardner_confidence_table data (deprecated in 585e7b4).
  • Updated get_cov_ZIP_ML() to match expressions on manuscript, introducing minor calculation optimisation.
  • Improved fit_maxlik_method() by removing unused local variables and redundant calls.
  • Switched message() to cli::cli_alert_warning() in fit() function when switching from glm() to ML optimization.
  • Updated match_names() to return input x, akin to match.arg() from {base}.
  • Updated default values for assessment and whole-body error method selection in mod_estimation_micro_ui().
  • Added mean and std_err column renaming to calculate_aberr_table() when type = "case" depending on new aberr_module parameter.
  • Added aberr_module validation using match.arg() in *_aberr_table(), estimate_*(), prepare_maxlik_count_data(), fit*() functions.
  • Updated unit tests for names_from_model_formula() and parse_model_formula().
  • Updated app_config.R and test-golem-recommended.R unit tests.
  • Added unit test for load_rmd_report().
  • Added basic testServer() unit tests for all mod_*_server() modules.

UI Improvements

  • Updated “Irradiation conditions” boxes so they are no longer collapsed by default in mod_fitting_*_ui.R modules.

Bug fixes

Deprecations

  • Removed unused files in data-raw.
  • Deprecated model_formula with no intercept in parse_model_formula(), names_from_model_formula(), prepare_maxlik_count_data(), fit_maxlik_method(), and mod_estimation_fit_curve_hot_server().
  • Removed golem_utils_server.R.
  • Purged calculate_decision_threshold*() functions and mentions in UI and server modules, as this will be rewritten from scratch.
  • Removed calculate_decision_threshold from _pkgdown.yml.

biodosetools 3.6.0

CRAN release: 2022-01-27

  • Major rewrite of plot_estimated_dose_curve() function.
  • Delta method calculations are now all done via msm::deltamethod().
  • Added progress and alert notifications to UI.
  • Added {markdown} as suggested dependency.
  • Added {cli} as dependency.
  • Tweaked references section in {pkgdown} site to only include exported functions organised by topic/usage.
  • Use consistently genomic conversion factor or genome_factor across all functions, help dialogues, and reports.
  • Added R-CMD check GitHub Action.
  • Added vignettes.

New features

  • Return conf_int in estimate_*() family of functions.
  • Parse est_full_doses$type in plot_estimated_dose_curve() function so unused assessments are not shown in legend.
  • Added match_names() function to match est_doses list names when calling plot_estimated_dose_curve().
  • Updated plot_estimated_dose_curve() to automatically build est_full_doses object from list of dose estimation results, added parse_conf_int_text() auxiliary function.

Bug fixes

New functions

Improvements

  • Fixed order of output case data columns in calculate_aberr_table() so they match the final output in Shiny.
  • Renamed count-data-IAEA.csv to count-data-barquinero-1995.csv from Barquinero et al. (1995) https://doi.org/10.1016/0027-5107(94)00150-4.
  • Added count-data-rodriguez-2004.csv for total translocations from Rodriguez et al. (2004) https://doi.org/10.1667/RR3198.
  • Updated translocations fitting unit tests to use data from Rodriguez et al. (2004) https://doi.org/10.1667/RR3198.
  • Rewrote calculate_aberr_power() to remove {purrr} dependency and reduce computation time by 4.
  • Replaced message() calls with appropriate cli::cli_*() calls.
  • Split quasi-Poisson from automatic fitting in fit_glm_method(), as it is otherwise confusing.
  • Updated \sigma to \hat{\sigma} in fix_count_data_names() and respective tests.
  • Updated unit tests to test individual values both in dose-effect fitting and dose estimation.
  • Use *-fitting-results-*.rds instead of *-fitting-data-*.rds when exporting RDS objects in mod_fitting_results_server().

UI Improvements

  • Added new side-widget-* CSS classes to better style file download/format buttons.
  • Added widget_sep_vert() function.
  • Use new sep-widget_* CSS classes in fitting UI modules.
  • Updated report help modals text.
  • Using new side-widget-* CSS classes in dose estimation UI modules.
  • Added progress notifications to calculations via shiny::Progress.
  • Updated _pkgdown.yml and simplified extra.css thanks to Bootstrap 5 support in {pkgdown} 2.0.0.

biodosetools 3.5.0 (2021-05-26)

  • Added unit tests for to check code coverage and to validate that the code performs as expected.
  • Major revision of the fitting and dose estimation pipelines, introducing new auxiliary functions to reduce duplicated code.
  • Major simplification of report rendering process; abandoned HTML output.
  • Added custom {pkgdown} theme for more consistent branding.
  • Added preliminary citation to README.
  • Moved packages required only for reports to Suggests field in DESCRIPTION file.

New features

  • Added irradiation conditions input to dose-effect fitting modules.
  • Reports include conditional formatting of u-value and other formatting refinements.
  • Added biodosetools_version element to Shiny App’s exported *-fitting-data-YYY-MM-DD.rds files.
  • fit() function allows to optionally select "glm" or "maxlik" algorithms. If "glm" if selected, the original tryCatch() routine will be executed.

Bug fixes

  • Fixed unexported calculate_aberr_var() function.
  • Stopped using weights in fitting algorithms (glm and glm.nb). Fixes #20, addresses part of #14 as well.
  • Fixed aggregated count data column parsing in fix_count_data_names() function.
  • Fixed case data parsing issue when .csv file is not perfectly formatted.
  • Fixed issue with manual fitting curve input (fixes #23).
  • Fixed bug in calculate_yield_infimum() where infima were being calculated for yield estimate only (fixes #26).
  • Fixed wrong calculation of aberrations X for Ck when k>=10 (fixes #27).
  • Fixed fix_count_data_names() to properly correct Ck>=C10 (related to issue #27).
  • Added “where” to global variables (see https://github.com/r-lib/tidyselect/issues/201).

New functions

  • inner_column(), to fix padding of boxes inside columns.
  • widget_sep(), to insert div(class = "widget-sep", br()) calls.
  • widget_sep_vert() to insert div(style = "height: 8px;") calls.
  • names_from_model_formula(), to parse rhandsontable() Unicode row and column coefficient names.
  • parse_model_formula() to get raw and TeX formulae from model_formula.
  • calculate_trans_rate_sigurdson() and calculate_trans_rate_manual() to calculate translocation rates.
  • calculate_aberr_table() wrapper, to calculate aberration tables for count and cases data.
  • init_aberr_table(), to initialise aberration distribution tables in fitting and estimation server modules.
  • list_fitting_formulas(), to replace global global_fitting_formulas object.
  • generalise_fit_coeffs() and generalise_fit_var_cov_mat(), used internally in estimation functions instead of using general_fit_* as parameters.

Function refactoring

  • Refactored get_decision_threshold() function to calculate_decision_threshold(), and added calculate_decision_threshold_table() wrapper function.
  • Refactored calculate_decision_threshold_*() functions to remove input argument.
  • Refactored get_*() translocation functions to calculate_*() for better consistency.
  • Refactored get_*_dose_curve() functions to plot_*_dose_curve() for more clarity.
  • Refactored get_model_statistics() to calculate_model_stats().
  • Refactored get_fit_*() functions to fit() and fit_*_method().

Improvements

  • Added Oliveira citation on get_fit_maxlik_method() function.
  • Fixed Gaëtan’s name order in citation and contributors list.
  • Updated README and About body text.
  • Renamed source R files for better naming consistency.
  • Changed structure of modules to mod_<calc_type>_<aberration>_*().
  • Generalised get_model_statistics() function so that local get_model_statistics() definition could be removed from mod_estimate_fit_curve_server() module.
  • Multiple (18 files) <aberration>-<module>-<format>.Rmd report templates have been merged into <module>-<format>.Rmd (4 files).
  • Use correct_negative_vals() to ensure correct dose estimation when X < Xc in translocations assay.
  • Replaced all *_at() and *_if() occurrences by their {dplyr} 1.0.0 equivalents.

UI Improvements

  • Replaced column(width = X) calls by col_X() in UI modules.
  • Added tabitem-container class to tabItem() page containers for fixed max-width while keeping responsive UI.
  • Added col-inner-textinput-* CSS classes for Irradiation conditions textInput() widgets’ containers.
  • Added sep-widget-download and sep-widget-format CSS classes to unify download and format select buttons into a single widget.

biodosetools 3.4.0 (2020-10-11)

  • Removed all non-ASCII characters.
  • Major overhaul of reports.
  • Added “Report bug” button on home screen and cleaned up dashboard_*() code.
  • Removed dependencies on {stringr} package.
  • Initial utils::citation() support via CITATION file.
  • Minimal version of R bumped to 3.5.0.
  • Minimal version of {dplyr} bumped to 1.0.0.

Bug fixes

  • Replaced C, α, β variables (and derivatives) by coeff_C, coeff_alpha, coeff_beta.
  • Fixed error in genome_fraction parsing for translocations in estimate_partial_dolphin().
  • Fixed count/case data standard error column names replacements.
  • Fixed minipage issue when using more than 12 columns in {knitr} tables with column name replacements, by using format = "latex", escape = FALSE parameters in kable() call.
  • Suppress YAML warning when using !expr in PDF reports. See https://github.com/rstudio/rstudio/issues/7545.

New functions

  • fix_coeff_names(), to fix coefficient names in reports.
  • fix_count_data_names(), to fix count/case data column names in PDF reports.
  • to_title(), to replace stringr::str_to_title() using base R.

Reports improvements

  • New PDF reports, which are now the default output format.
  • Improved HTML reports styling.
  • Added explicit M-FISH usage in translocation reports.
  • Added assay name in report titles.

biodosetools 3.3.1 (2020-10-07)

Bug fixes

  • Count and case data calculations are performed using calculate_aberr_*() functions. Fixes #8.
  • Fixed missing {dplyr} namespace in n() function call.
  • Fixed mismatched use of awesomeCheckbox() and switchInput() in confounders input.

New functions

biodosetools 3.3.0 (2020-07-27)

Initial migration of the app into a {golem} R package. This means Biodose Tools is also available as a regular R package in case the user wants to build their own R scripts. This also reduced lots of code redundancies, and made the code a lot more robust.

New features

  • App is now a {golem} R package.
  • Migrated UI from {shinydashboard} to {bs4Dash}.
  • Modals are now built with {bsplus} instead of {shinyBS}.
  • Functions and internal data are documented using {roxygen2}.
  • Added {pkgdown} support to build {biodosetools}’s website automatically.
  • All custom theming is done through SASS and CSS instead of R code injection.

New functions

  • New include_help() for help dialogues
  • New help_modal_button() function to help build modal trigger buttons on boxes’ titles.
  • New load_rmd_report() function to use in server downloadHandler().
  • Moved get_genome_fraction() as its own exported function.

Fixes

  • Fixed #7. Overestimate error of lambda when dispersion is smaller than 1.
  • Fixed missing icon on sidebar.
  • Fixes in collapse button paddings.
  • Fixed tabBox parameters.
  • Using rlang::.data$ to avoid “no visible binding for global variable” warnings.
  • Fixed bsplus::bs_modal() calls in output$estimate_results_ui.
  • Removed input as parameter in calculation functions.
  • Fixed style of help button on box/tabBox headers.
  • Updated old “biodosimetry-uab” URLs to “biodosetools-team”.

Improvements

  • Stop exporting auxiliary include*() functions used on the app only.
  • Moved widget_label() to widgets.R.
  • Refactored inner_column() function.
  • Refactored UI modules names.
  • Refactored server functions and renamed R scripts.
  • Updated reports.
  • Using load_rmd_report() on mod_estimate_results_server() module.
  • Added DNA Content Fractions of Human Chromosomes (IHGSC) data.
  • Updated dna_content_fractions call on mod_trans_fraction_to_full_genome_server() module.
  • Added support for tabBox on help_modal_button() widget.
  • Added indentation to all module rhandsontable() calls.
  • Stop exporting get_decision_threshold() function temporarily.
  • “Stains color options” boxes don’t use inner_column() anymore.
  • Updated NEWS.md headers so they can be parsed by {pkgdown}.

UI Improvements

  • Removed experiment_select selectInput() from sidebar. Every assay is listed on the “Aberration assays” sidebarMenu().
  • Loading all UI modules in dashboard_body().
  • Navbar now uses rightUi and leftUi parameters, as well as skin = "light".
  • Switched from shinyBS::bsButton() to shiny::actionButton() for calling modal dialogues.
  • New CSS style sheet for {shinydashboard}.
  • Deleted old CSS files for {bs4Dash}.
  • New fonts CSS stylesheet.
  • New CSS stylesheets for fixes of existing classes and definition of custom classes.
  • Added hot-improved CSS class for rHandsontableOutput().
  • Moved custom widgets classes from theming.R to custom.css.
  • Tweaks in box, awesome-checkbox, and sidebar submenus CSS styles.
  • Replaced theme_button_status() function by proper SASS to CSS compilation.
  • Finished SASS box header colors.
  • Using SASS modules to reconstruct biodose_style.css.
  • Moved treeview-menu style to sidebar.scss.
  • Added checkboxes SASS style.
  • Added missing col-inner-* CSS classes.
  • Added app version on sidebar footer with custom sticky-footer CSS class.
  • Switched to a single stylesheet, being everything built by SASS modules.
  • Added custom style to radiobuttons.

biodosetools 3.2.1 (2020-02-13)

Bug fixes

  • Added required {pander} package to generate DOCX reports.

biodosetools 3.2.0 (2020-02-11)

All calculations functions previously provided in inst/app/calcs have been made proper functions on the package.

New functions

“New” functions

biodosetools 3.1.0 (2019-10-26)

Unofficial release (wasn’t changed on DESCRIPTION file). This includes some of the changes discussed with David in Stockholm (ERPW19).

New features

  • Made var-cov matrix optional on dose estimation inputs.
  • Fixed calculations to make var-cov matrix optional on dose estimation inputs.

Fixes

  • Added additional package dependencies to DESCRIPTION file.
  • Following the ISO, renamed detection limits to decision threshold.

Changes

  • Disabled decision thresholds (for now).
  • Hide AIC as a relative quality statistic of the dose estimation.
  • Added mean and variance to count data tables in fitting module.

biodosetools 3.0.0 (2019-10-12)

The app is now available as an R package on GitHub (not submitted to CRAN yet).

New functions

  • runApp() for launching Biodose Tools.
  • %>% imported from {magrittr}.

Fixes

  • Fixed variance calculation for count data.
  • Provide fallback method for NB2 when using constraint-maxlik-optimization.

biodosetools 2.1.0 (2019-07-27)

New features

  • Initial implementation of micronuclei, adding support in UI and server functions.
  • Implemented negative binomial fitting calculation for micronuclei count data.
  • Initial detection limit implementation for translocations.
  • Added DOCX support for dicentrics and translocations.

New functions

  • New bs4MyTabPanel() widget to remove unnecessary padding on tabCards’ panels.

Fixes

  • Fixed colwidths for detection limits.
  • Fixed unnecessary recalculation of num_cols for chromosome tables in translocations modules.
  • New subdirectory structure for help dialogues.
  • Added buttons and example tables in help dialogues.
  • Updated documentation link.

Improvements

  • Added button_fit dependency for detection limits calculation.
  • Updated fitting reports (new hot structures & dynamic widths).
  • Moved calculation functions from fitting and estimation modules to their own files in a new calcs directory.
  • Translocations reports are complete now.

Changes

  • Disable sourcing translations.R for now (until {shiny-i18n} is implemented).

biodosetools 2.0.0 (2019-07-17)

New features

  • Added manual input of translocations name.
  • Implemented dynamic calculation of hot width for counts, cases, and chromosome data tables.
  • Implemented manual input of translocation frequency to be subtracted from the observed yield.
  • Started detection limit calculation in fitting module.
  • Implemented Delta method for whole-body estimation.
  • Added calculation of standard error of Fg for translocations’ dose estimation module.

Fixes

  • Fixed dependency of the “Calculate fitting” button in the translocation module.
  • Fixed calculations for whole and partial body estimations for translocations module.
  • Fixed colors on chromosome hot table example.
  • Fix genomic conversion factor not being read when doing fitting.
  • Fix Fp -> y when using dicentrics in dose estimation module.
  • Fixed detection limit calculation.
  • Fixed dose estimation in detection limits function.
  • Corrected correction of FISH to Full genome when inputting manual fitting curve in dose estimation modules.
  • Corrected reading of translocations fit curve values in dose estimation module.

Improvements

  • Tweaked variable names and order in cases data for translocations dose estimation.
  • Updated help_colors_dialog for translocations modules.
  • New module for auxiliary rhandsontable() tables used in help dialogues.
  • New help dialogues for translocations modules.
  • Consistent use of genome_fraction in variables related to the genomic conversion factor/fraction of genome hybridised.
  • ggplot2 curve generation is now wrapped inside a function on the dose estimation modules.
  • Finished confounders help dialogue.
  • New aberration calculation method using purrr::map_df() instead of a nested loops, which is about 10 times faster.
  • Make clear in translocations dose estimation module that the coefficients are from the full genome.
  • Added highly protracted exposure.
  • Implemented calculation of detection limits from data.
  • Added dose calculation to detection limits section.
  • Changed σ to \sigma in help dialogues.
  • Added units to result tables.
  • Code clean-up on delta method for whole-body dose estimation.
  • Updated plot CI text generation on legend to account for new Delta method and for separate whole-body & heterogeneous error method selection.
  • CONTRIBUTORS.md is now displayed as a modal.
  • Using ORCID for authors when possible.
  • Updated institution links in contributors files.

UI Improvements

  • Improved side-widget-tall bottom margins.
  • Moved translocation frequency selectInput() next to Calculate Fitting button for better UX.
  • New hot-improved CSS class for better hot tables’ formatting.
  • All hot tables are using hot-improved class now.
  • New contributors list style and custom CSS style for tables.
  • Added experiment/aberration name on tab body title to avoid confusions.
  • Improved “About” tab paddings.
  • Improve widths of color columns in chromosome tables.
  • Narrower color columns in chromosome tables.
  • All hot tables’ widths are dynamic or exact now.
  • Improved small action buttons style on help dialogues.
  • New results color to differentiate from main color.
  • Updated UI to adapt for new Delta method for whole-body estimation.
  • Updated translocations UI to adapt for new Delta method for whole-body estimation.
  • Added CI for Dolphin dose estimation UI.
  • Added (work in progress) Micronuclei into UI.
  • Hide language selector until shiny-i18n is implemented.

biodosetools 1.2.0 (2019-06-25)

New features

  • Start translocations dose estimation module and report.
  • Allow using M-Fish color scheme in translocations fitting module.
  • Added method to convert from translocations measured by FISH to full genome.
  • Implemented confounders modifications for translocations in generalEstimateCaseHotTable() module.

Improvements

  • New chromosome table structure. transChromosomeTable() and transFractionToFullGenomeCalc() have been moved to transGeneralModule.R, as they are reused in the dose estimation module.
  • Using new chromosome table UI and server modules for translocations dose estimation.
  • Merged “repeated” fitting modules into a generalFittingModules.R file.
  • Merged *FittingResults() modules into generalFittingResults() module.
  • Updated translocations fitting report to new chromosome table structure.
  • New generalEstimateFittingCurveHotTables() and generalEstimateFittingCurve() modules.
  • New globalVariables.R with global_fitting_formulas list.
  • Added translocations-specific code in generalEstimateFittingCurve() module to take into account used translocation frequency.
  • New inputs for used translocation frequency and genomic conversion factor in manual fitting input in dose estimation module.
  • Moved dose estimation to generalEstimateResults() module.
  • Modify translocations (X - Xt) for whole-body and partial-body dose estimation.
  • Added readOnly status to Xt, yt, yt_err variables on rhandsontable() for translocations case data.

UI improvements

  • New innerColumn to use inside cards/boxes.
  • New widgetLabel() function for labels above widgets without default label.
  • Replaced old labels by new widgetLabel() function.
  • Finished confounders UI in translocations dose estimation module.
  • New mySwichInput() function based on shinyWidgets::switchInput() with sideLabel and custom status colors.
  • Moved from awesomeCheckbox() to mySwitchInput() in all UI modules.
  • Moved fitting curve input in translocations’ dose estimation module to the top.

Fixes

  • Fix minor error in calculation of infimum yield values.
  • Fixed “Color options” card and color_list object for chromosome table generation.
  • Fixed missing type argument in get_model_statistics() in dose estimation module.
  • Deleted heterogeneous estimation for translocations.

biodosetools 1.1.0 (2019-06-15)

New features

  • Conditional tabs in sidebar by implementing bs4MyConditionalSidebarMenuItem() function.
  • Implemented AIC calculation for different dose estimation assessments.
  • Added ZIP archive with sample data for testing.
  • New dynamic bs4TabCard() using renderUI() and session$ns() to show different tabs depending on user input.
  • Implemented manual calculation of case parameters (N, X, y, y_est, DI, u) in dose estimation module.

Improvements

  • Disabled automatic calculation of N, X, DI, u to avoid broken input issues when running the deployed app.
  • Added CONTRIBUTORS.md file.
  • Removed {fontawesome} package requirement.
  • Added translocation frequency and genomic conversion factor to translocations fitting report.
  • Chromosome table included in reports.
  • Major rewrite of {ggplot2} plot in dose estimation module.
  • Added Dolphin CI info into plot when using partial-body assessment.
  • Changed display of CI in plot for dose estimation.
  • Genomic conversion factor is used in transFittingResults() module for calculations instead of modifying the value of N in transFittingHotTable().
  • Added theoretical calculation of model-specific statistics (glm method) on fitting module.
  • Added renormalisation of data for proper calculation of model-specific statistics in fitting module.
  • Added theoretical model-specific statistics calculation for constraint maxlik optimization method in fitting module.
  • Added global get_model_statistics() to translocations fitting module.

UI improvements

  • Cleaner version of topButton() for help button and help modals on fitting and dose estimation modules..
  • More informative model summary dialogue in fitting module.
  • Better output of genomic conversion factor.
  • “Partial” is now “Partial-body”. Better titles in dose estimation results card.
  • New bs4MyTabCard() function with topButton and noPadding capabilities.

Fixes

  • Fixed problem with fit_formula_raw when using linear model. Disabled *-no-int models until Dolphin can deal with them.
  • Fixed rendering problem in Firefox (and potentially other browsers) with count data rhandsontable() using 100% of the card’s height.
  • Fixed dose estimation rhandsontables() divs on Firefox having height = 100% of the card’s own height.
  • Fixed height error in cases data table in dose estimation module in Firefox.
  • Fixed glm_results object issue in get_model_statistics() function.

biodosetools 1.0.0 (2019-05-24)

First public beta for laboratories and research centres.

New features

  • Initial support of reports.
  • Implemented selection of CI for dose estimation (83%-83% & 95%-95%).
  • Added method selection for partial body exposure estimation.
  • Fixed formatting of variance covariance matrices when rendered by rHandsontableOutput().
  • Linear models compatibility for partial-body (Dolphin) and heterogeneous dose estimation.
  • Experimental version of new Maximum Likelihood Estimation method for dose-effect fitting.
  • Manual input of fitting coefficients and var/cov matrix for dose estimation.

Improvements

  • Added format/MIME type validation for file inputs.
  • Render fitting formula using MathJax.
  • Format curve depending on selected assessment/method (use appropriate CI) on dose estimation.
  • Check if yield projection into dose is mathematically possible. Negative values of yield or dose are changed to zero as well.
  • Added modification to Merkle’s yield error function when using protracted exposures.
  • Implemented protracted exposure for partial body dose estimation.
  • Added automatic Poisson/quasi-Poisson selection on fitting.
  • Correct p-values depending on fitting model dispersion.
  • Added automatic correction of confidence intervals to use “simplified” Merkle’s method if necessary.

Fixes

  • Fixed calculation of full genome.
  • Fixed alignment of conditional error/method inputs for dose estimation.
  • Changed “base” to “estimate” on CI tables for dose estimation.
  • Fixed bs4TabCard() bug.

biodosetools 0.2.0 (2019-04-03)

Version presented in second Team Meeting at Munich.

New features

  • Migrated UI from {shinydashboard} to {bs4Dash}.
  • Added data, plot, and results export options.
  • Added modal dialogues using {shinyBS}.
  • Dose estimation modules for dicentrics.
  • Complete implementation of dicentrics analysis.
  • Experimental fitting for translocations assay.

biodosetools 0.1.0 (2018-11-29)

First draft and proof of concept presented to the RENEB team at Barcelona.

Features

  • UI built using {shinydashboard}.
  • Fitting modules for dicentrics.
  • Dynamic input tables powered by {rhandsontable}.