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Shiny app

Run Biodose Tools Shiny app.

run_app()
Run the Shiny Application

Fitting

Fit and visualise calibration dose-effect curve.

fit()
Perform dose-effect fitting algorithm
plot_fit_dose_curve()
Plot fit dose curve

Dose estimation

Estimate and visualise uncertainties on dose estimations.

estimate_whole_body_merkle()
Whole-body dose estimation (Merkle's method)
estimate_whole_body_delta()
Whole-body dose estimation (delta method)
estimate_partial_body_dolphin()
Partial-body dose estimation (Dolphin's method)
estimate_hetero_mixed_poisson()
Heterogeneous dose estimation (Mixed Poisson model)
plot_estimated_dose_curve()
Plot dose estimation curve

Auxiliary

Auxiliary functions used in the fitting and dose estimation pipelines.

calculate_aberr_table()
Calculate aberrations table
protracted_g_function()
Calculate protracted function \(G(x)\)
calculate_genome_factor()
Calculate genomic conversion factor
calculate_trans_rate_sigurdson()
Calculate Sigurdson's translocation rate
calculate_trans_rate_manual()
Calculate manual translocation rate