Delta method for approximating the standard error of a transformation \(g(X)\) of a random variable \(X = (x1, x2, ...)\), given estimates of the mean and covariance matrix of \(X\).
Usage
get_deltamethod_std_err(
fit_is_lq,
variable = c("dose", "fraction_partial", "fraction_hetero"),
mean_estimate,
cov_estimate,
protracted_g_value = NA,
d0 = NA
)Arguments
- fit_is_lq
Whether the fit is linear quadratic (
TRUE) or linear (FALSE).- variable
Variable resulting of the transformation \(g(X)\).
- mean_estimate
The estimated mean of \(X\).
- cov_estimate
The estimated covariance matrix of \(X\).
- protracted_g_value
Protracted \(G(x)\) value.
- d0
Survival coefficient of irradiated cells.